The drug delivery research is
offered in the area of oral-controlled
release-systems. There are products currently
under development in this area using patented
'Platform Technologies’.
ARC is capable of developing various
technologies, which can be highlighted as
follows:
Swellable Gastro-floating Systems
A cohesive gel develops in-situ with sufficient
strength to withstand the churning action of the
stomach. This gel development is based on the
reacting species causing gas generation (e.g.
Carbonates along with swellable polymers like
cellulose, carbomers, natural gums)
Osmomicrosealed Gastroretentive Drug Delivery
The swellable osmo microsealed drug delivery
system can be developed at ARC whose unique
feature is swelling to a size greater than 9 mm
(The pylorus diameter) and thereby, by the
virtue of geometry it is retained in stomach
Pelletization drug delivery
Pelletization is an agglomeration technique that
converts fine powder or granules of bulk drugs
and excipients into small, spherical free
flowing units, referred as pellets.
ARC has expertise in pelletized drug delivery
system for various products. Presently, pellets
are being developed for delayed release and
sustained release dosage forms.
Taste Masking
Taste is an important parameter governing
patient compliance. Several oral pharmaceuticals
have unpleasant bitter-tasting components. The
desire for improved palatability of these
products has prompted the development of
numerous formulations with improved performance
and acceptability.
ARC is offering a unique taste masking
technology. This technology makes it possible to
mask the unpleasant taste of some active
principles and reduce the irritation caused on
the mucosa of the mouth, without reducing the
degree and speed of absorption.
Focus Areas of Development in NDDS
ARC offers Novel Drug Delivery Systems focused
at following therapeutic areas: